Actifed Multi-Action Dry Coughs 100ml

Multi-Action ACTIFED Dry Coughs contains 1.25 mg triprolidine hydrochloride, 30 mg pseudoephedrine hydrochloride and 10 mg dextromethorphan hydrobromide in each 5 ml.

Triprolidine may cause drowsiness and patients should not drive or operate machinery until they have determined their own response.

Central nervous system depression or excitation may occur, drowsiness being reported most frequently. Sleep disturbance and rarely, hallucinations have been reported.

Skin rashes, with or without irritation, tachycardia, dryness of mouth nose and throat have occasionally been reported. Urinary retention has been reported occasionally in male patients in whom prostatic enlargement could be an important predisposing factor.

Side effects attributed to dextromethorphan are uncommon; occasionally nausea, vomiting or gastro-intestinal disturbance may occur.

Caution should be exercised when administering Multi-Action ACTIFED Dry Coughs to patients with severe hepatic impairment.

Caution should be exercised when administering Multi-Action ACTIFED Dry Coughs to patients with moderate to severe renal impairment.

Multi-Action ACTIFED Dry Coughs is contraindicated in individuals who have previously exhibited intolerance to it or to any of its constituents.

Multi-Action ACTIFED Dry Coughs is contraindicated in patients with severe hypertension or severe coronary artery disease.

Multi-Action ACTIFED Dry Coughs is contraindicated in individuals who are taking, or have taken, monoamine oxidase inhibitors within the preceding two weeks. The concomitant use of pseudoephedrine and this type of product may occasionally cause a rise in blood pressure.

The antibacterial agent, furazolidone, is known to cause a dose-related inhibition of monoamine oxidase. Although there are no reports of hypertensive crises caused by the concurrent administration of Multi-Action ACTIFED Dry Coughs and furazolidone they should not be taken together.

Multi-Action ACTIFED Dry Coughs should not be administered to patients where cough is associated with asthma or where cough is accompanied by excessive secretions.

Dextromethorphan, in common with other centrally acting antitussive agents, should not be given to patients in, or at risk of developing respiratory failure.

Multi-Action ACTIFED Dry Coughs may cause drowsiness, and impair performance in tests of auditory vigilance. Patients should not drive or operate machinery until they have determined their own response.

Although there are no objective data, users of Multi-Action ACTIFED Dry Coughs should avoid the concomitant use of alcohol or other centrally acting sedatives.

Although pseudoephedrine has virtually no pressor effects in patients with normal blood pressure, Multi-Action ACTIFED Dry Coughs should be used with caution in patients taking antihypertensive agents, tricyclic antidepressants, other sympathomimetic agents such as decongestants, appetite suppressants and amfetamine-like psychostimulants. The effects of a single dose of Multi-Action ACTIFED Dry Coughs on the blood pressure of these patients should be observed before recommending repeated or unsupervised treatment.

As with other sympathomimetic agents, caution should be exercised in patients with hypertension, heart disease, diabetes, hyperthyroidism, elevated intra-ocular pressure or prostatic enlargement.

There have been no specific studies of Multi-Action ACTIFED Dry Coughs in patients with hepatic and/or renal dysfunction Multi-Action ACTIFED Dry Coughs should be used with caution in patients with liver disease.

There have been a few reports of abuse of dextromethorphan but there is no evidence of drug dependence at therapeutic dosages.

Not more than 4 doses should be given in any 24 hours.

Do not exceed the stated dose.

The packs carry the following statements

Warning: May cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.

If you are pregnant or currently taking any other medicine, consult your doctor or pharmacist before taking this product.

If symptoms persist consult your doctor.