Malaria Region Dox/Mal only

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Malaria Region Dox/Mal only - For this region there is a choice of only

malarone tablets

Generic Malarone - Atovaquone/Proguanil 250mg/100mg

OR

doxycycline capsules

to prevent malaria in adults. (Lariam is not recommended due to resistance in this region.) The choice of medicine fromn the two above will depend on your medical history, current medication and length of visit.

 

Malaria medication4

 

malaria prevention4

 

Important information:

It is highly recommended that you use a DEET containing mosquito repellent in addition to your anti-malaria medication. 

General Information:

  • Always use the correct medication for the areas you are travelling to.
  • If you are travelling between areas that require different medications then discuss the itinerary with your doctor.
  • Always discuss child medication with your doctor.
  • Always complete the course of medication unless advised by a doctor.
  • ALWAYS TAKE EXACTLY AS PRESCRIBED. STOPPING MEDICATION OR CHANGING THE DOSAGE IS NOT ADVISABLE.
  • Seek medical advice if you experience side effects to any antimalarial medication. 

Things you might need for your trip:

Oral rehydration, antidiarrhoea capsules, sun cream, aftersun, travel sickness, anti deep vein thrombosis measures ( low dose aspirin, travel socks), Insect bite treatments, travel first aid kit, your regular medication, sun hats.

 

Adult Dosages:

doxycycline capsules

1 x daily (1 x 100mg capsule) Take 1 or 2 days before travel, throughout stay and for four weeks after return.

OR

malarone tablets

Generic Malarone - Atovaquone/Proguanil 250mg/100mg

1 x tablet daily. Take 1-2 days before travel, throughout stay and for seven days after return.

Long-term Travel

Doxycycline can be taken for up to two years.
Malarone is currently licensed for periods of stay not exceeding 28 days, but there is now experience of it being taken safely for up to one year. 

PRECAUTIONS

Doxycycline can alter the metabolism of oral contraceptives. Patients using an oral contraceptive should take extra contraceptive precautions for the first three weeks after starting long-term antibiotics. After three weeks, gut flora develops antibiotic resistance and additional precautions become unnecessary. Rarely Doxycycline can cause photosensitivity (sensitivity to sunlight) in patients taking it at doses for malaria prophylaxis, it is normally mild and can be minimised by using high factor sunscreens.

PSORIASIS
Doxycycline and Malarone do not cause any problems in patients with psoriasis.

HEPATIC OR RENAL IMPAIRMENT
All patients with hepatic or renal impairment should be referred to their specialist, as we will not know the degree of your condition.

PREGNANCY
Travel to malarious zones during pregnancy should be avoided. However, if travel is unavoidable, effective prophylaxis should be used as malaria is more severe during pregnancy and the risk of malaria to mother and foetus is greater than the risk from any antimalarial drugs at the recommended doses.  All pregnant travellers should see their doctor.
Doxycycline is contra-indicated during pregnancy.
Malarone should be avoided because its safety in pregnancy has not been established.

BREASTFEEDING AND BREASTFED INFANTS
Prophylaxis is still required in breast-fed infants; although anti-malarials are excreted in breast milk, the amounts are too variable to give reliable protection. Doxycycline and Malarone are contra-indicated in lactation.

This page was last updated: Monday 25 September, 2017